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Infectious Diseases and IPT

        One of the most successful and promising applications of insulin potentiation therapy (IPT) is  in the treatment of a wide variety of infectious diseases, whether viral, bacterial, or parasite-caused.    I have created sections on IPTQ for  these, as well as a page for sexually-transmitted diseases (STDs).  At this point I do not have records of any cases of known fungal infections treated by IPT, but I'll bet that Dr. Perez Garcia y Bellon 2 had some.  

        Dr. Perez Garcia 1's very first application of IPT was to treat an infectious disease, syphilis.  Over more than 130 doctor-years, IPT has had very successful and sometimes spectacular results in treating many different infectious diseases, including some of the most serious threats to human life and quality of life.  Based on this long and diverse track record, we can expect that still more diseases will be found to be treatable with unprecedented effectiveness with IPT.  

        Even some diseases that have previously been thought to be noninfectious in origin may actually have an infectious cause, and IPT could be an optimal way to fight these infections.  Heart disease.  Alzheimer's.  Cancer.  Mental illnesses.  Continue to the next section for more on this.

        Here on IPTQ I propose a protocol of multi-pathogen IPT  (MP-IPT) treatments as a way to simultaneously clear the body of many bacteria and viruses, detectable or not, that could be underlying a wide variety of disease symptoms, and to prevent development of more.

        And IPT could be a tool to address problems of the rapid evolution of drug resistance in bacteria and viruses.

Viral ] Bacterial ] STDs ] Parasites ]

Possibilities:

Chronic diseases -- infectious origin?

        Evolutionary microbiologists and epidemiologists, most notably Amherst College biologist Paul Ewald, have been working on a theory that many supposedly noninfectious chronic diseases may actually have an infectious origin.  Here is an excellent article about this theory ("A New Germ Theory", by Judith Hooper, Atlantic Monthly, February 1999), which is the basis of much of the discussion that follows  The basic idea is that any hereditary disease will be removed from the population over time, down to the level of random mutation.  So any serious chronic disease that has been around for a long time is probably not due to heredity, but most likely due to infection.

        Ulcers are cited as a major example.  Long thought to be due to stress, diet, and other causes, they were recently found to be caused by a bacterium, Helicobacter pylori, with a course of antibiotics being the most effective treatment.  

         Note that Dr. Perez Garcia 1 demonstrated great success in non-surgically treating ulcers -- even ulcers with pyloric stenosis -- with antibiotics potentiated with IPT, back in the 1950s,  long before the discovery of the causal bacterium.  Unfortunately, he was ignored.  IPT could still offer faster treatment for ulcers, I believe.   See the Ulcers page.

Now other diseases are suspected of being at least partly infection-caused:

Positive results have been reported recently for treatment of resistant  chronic fatigue syndrome (CFS) and fibromyalgia using IPT along with antiviral drugs.   
Articles 1 2 3.

For heart disease and atherosclerosis, they suspect infection by the bacterium Chlamydia pneumoniae, and perhaps other bacteria found in dental plaque.

For Alzheimer's disease, perhaps Chlamydia pneumoniae, also.

Some, forms of cancer appear to have infectious origin, and many more, if not most, may be found to have this origin.  HTLV-1 virus is associated with some leukemias and lymphomas.  Epstein-Barr virus is associated with some types of lymphoma and nasopharyngeal cancerHelicobacter pylori, the bacterium that causes ulcers, increases stomach cancer risk by a factor of six.  One type of stomach cancer is cured in 50 percent of cases through antibiotic treatment for the ulcers.  Hepatitis B and C are linked to liver cancerCervical cancer is highly associated with human papilloma virus infection.  Herpes virus 8 causes Kaposi's sarcoma.  DNA sequences resembling mouse mammary tumor virus (MMTV) have been found in human breast tumors.

Mental illnesses of several types may have infectious origin.  Streptococcus infection could cause obsessive compulsive disorder, either directly or due to a stimulated immune response.  Schizophrenia may be caused by Borna virus or a relative.  Depression is too common to be of genetic origin, Ewald thinks, and could have an infectious cause.  He thinks that even homosexuality may have an infectious origin, since it appears to work against species fitness and theoretically would not persist if it were of genetic origin

Multiple sclerosis (MS) may have infectious origin.  Some people think the cause could be herpes virus 6, and others think it could be a spirochete bacterium.

Rheumatic diseases.  See the Road Back Foundation website for discussion and a long-term low-dose antibiotic protocol for treatment of rheumatoid arthritis and other rheumatic diseases, including scleroderma, lupus, polymyositis, Reiter's syndrome, psoriatic arthritis, ankylosing spondylitis, and fibromyalgia.  The theory is that all these diseases are caused by immune reaction to chronic mycoplasma infection.

Obesity.  Strong evidence reported by Nikhil V. Dhurandhar, Ph.D. supports the idea that obesity can be caused or enhanced by Ad-36 adenovirus.

Other diseases cited by David Relman, Stanford professor of medicine , microbiology, and immunology, include "sarcoidosis, various forms of inflammatory bowel disease, rheumatoid arthritis, systemic lupus erythematosus, Wegener's granulomatosis, diabetes mellitus, primary biliary cirrhosis, tropical sprue, and Kawasaki disease."  And other diseases suspected by Paul Ewald and Gregory Cochran include  cerebral palsy, polycistic ovary disease, obesity, and some eating disorders.

        IPT has a long record of being extremely good at treating infectious diseases, including those like herpes and hepatitis C which are normally considered incurable because the virus hides in parts of the body.  So if many of these diseases have infectious origin, IPT could be positioned to become perhaps the most important of all medical methods.

Multi-Pathogen IPT treatment (MP-IPT)  --  a proposed protocol.

        Apparently microorganism infections may underlie most of the chronic diseases human beings suffer from, not just the known infectious diseases.   The trouble is that techniques for detecting most of these underlying infections are not yet known.  Much work remains to develop effective culturing and/or immunological tests.

        But you can bet that most of us probably have a lot of them.  My sense is that people go through life, picking up one infection after another from contact with family, friends, lovers, and strangers.  Most of these infections are controlled by the immune system, but many persist in hidden pockets within the body.  They may resurface later in life.  (Shingles is a good example, a resurfacing of herpes virus.)  Or they may interact with each other. (One theory is that AIDS is triggered from cumulative interactions of HIV and other infections).  They may trigger allergic and autoimmune reactions.  And they may cause any of the major chronic diseases that are suspected to be of infectious origin.   Eventually, one or more of these conditions gets out of control, and we die.

        What I am proposing is a protocol to "reset" the microbiological environment of the body, by using a course of IPT treatments in which smaller-than-normal doses of antibiotic, antiviral, antiparasitic, and antifungal medications are simultaneously potentiated.  I call it Multi-Pathogen IPT, or MP-IPT.  A broad spectrum of drugs would be used to treat a broad spectrum of detectable and undetectable infections.  This could take a major load off the immune system, relieve many symptoms and diseases, and prevent development of many more.  An important part of this "reset" would be an ongoing effort to re-implant the body with a full range of desirable bacteria.  The patient would then be sent back out into the world, healthier, older, wiser, certified, and highly motivated to avoid further infections.

        Actually, it is likely that this has been happening inadvertently during IPT, and could explain some of the remarkable observed improvements in health.  Treating one disease with antibiotics or antivirals, and stimulating the immune system with IPT, could certainly have cleared the body of other bacteria or viruses lying latent at the moment.  The difference here is that multiple drugs would be used simultaneously, with the stated intent of clearing both known and hidden infections.

Drug resistance and IPT...

        Bacteria and viruses evolve more rapidly than larger organisms.  So we are increasingly faced with microorganisms that have become resistant to one or more drugs.  Bacteria are evolving faster than we can develop antibiotics.  And viruses are evolving faster than we can develop antiviral drugs.  This evolution is speeded by two main trends:  using antibiotics to promote growth in livestock, and the tendency for unsupervised people to stop taking antibiotics or antiviral drugs before the disease is controlled.  This story is well known today.

IPT could offer a some partial solutions to this problem:

1.  IPT appears to make antimicrobial drugs work much better at standard doses, or just as well at much smaller doses.  This could extend the useful lifetime of antimicrobials, and thus buy us time in the microbe-drug war.

2.  IPT may increase patient compliance by making treatment shorter and more definitive.  If an infection is wiped out in one or two IPT treatments, the patient will will be less likely to stop taking the antimicrobial medication before the infection is controlled.

3.  IPT, by more effectively clearing the body of infection, may kill both resistant and nonresistant microorganisms equally, thus eliminating the evolutionary natural selection pressures of differential survival.

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