This is Act 2, where things don't turn out
the way you think. For the sake of website brevity I'll shift into fast forward...
Just the highlights.
The old house at 402 North Main Ave., Tucson.
SANA letterhead logo
I had been living with my dear grandmother,
Gladys Carroll, for 10 years, in the gracious house that her parents had built in 1898, at
402 North Main Avenue, in downtown Tucson. Her father was one of the founders of the
University of Arizona. 402 was (and still is) the last of the old anglo houses in
Tucson still occupied by the original family. She lived on the main floor, filled
with wonderful original furnishings and artworks. And I lived in the basement,
a tiny bachelor bedroom under the kitchen, and a large, chaotic office and lab under her
bedroom. I had finished my Ph.D. in that office, and had moved on to postdoctoral
courses, inventions, and other projects. That office now became the corporate
headquarters for SANA Institute, Inc. My friend Kathleen McCarthy, a young Tucson
lawyer (now one of the best and best known), was very kind to donate her time to help us
incorporate. There were lots of conference calls and letters in the mail. And
Dr. SGA created a logo and printed up cards for us all.
First SANA meeting with
Ft. Lauderdale, Florida, June, 1987.
(Standing L-R) Dr. Perez Garcia y Bellon 2, SGA MD.
(Seated L-R) Dr. Perez Garcia 3, Chris Duffield,
I dropped almost everything else in my life,
and jumped into SANA activities with all my heart. There was a trip to Fort
Lauderdale June of 1987, where Dr. SGA introduced Mel and me to
Drs. Perez Garcia 2 and 3,
and where I helped Mel polish the first patent application. We wrote and sent around
business plans. We signed an agreement with the Drs. Perez Garcia. We did a second
patent. We had tons more phone calls and letters between us. We wrote
and talked to lots of people. We redid the business plan. But the bottom
line is that we never attracted a single investor. The problem was that IPT is a
method, and we couldn't find a business model that would make it easy to make money from a
So then, in 1990, we decided to form a
nonprofit corporation. At least we could give IPT away, and be heroes, and make good
salaries, or so we thought. Thus, with the Drs. Perez Garcia included this time, we formed
Medical Renaissance Foundation, and went through all the expensive and time-consuming
steps to become a recognized 501-c(3) nonprofit organization. Again, it was an
Arizona corporation, with world headquarters in the basement of my grandmother's
house. I was the Vice Chairman of the Board this time. We had a stunning logo
and letterhead, designed by Wes Wait, a Portland, Oregon graphic artist I met through another
project, who did the work for free.
Kathleen McCarthy, when asked once what our
company was, replied that we were "a group of eccentric intellectuals".
Dr. SGA wrote papers and went to conferences, trying to get the idea of IPT out there for
breast cancer and AIDS. I did medical library research for Dr. SGA, and helped with
everything. Mel kept focusing on business leads and patent angles. And all of
us did a lot of phoning and meeting with possible funders, investors, researchers,
doctors, and patients. Here are some of the adventures I went through.
Button made by
SGA MD for our
IPT for AIDS initiative.
|[the classified ad]
AIDS & ARC Victims:
in Mexico City.
(for limited time).
Pay your own travel &
6 weeks expenses.
Serious applicants only
After the Drs. Perez Garcia
had success with IPT for
couple of AIDS patients, we decided to focus on the AIDS applications of IPT. In
1987 I met
with some AIDS organizers and a group of AIDS patients in Tucson, telling them about IPT.
I put a badly worded classified ad in the Tucson papers, offering free
treatment for AIDS & ARC "Victims" in Mexico City, with my home
phone number. But no one answered the ad. Then I traveled to San Francisco to meet with members of the AIDS medical treatment
underground. These were mostly men, mostly gay, who were searching the world for
better treatments, and were trying them. I told them about IPT, but it got nowhere.
Their doctors weren't interested. And no one wanted to go to Mexico
City for IPT
Later, Dr. SGA pushed for us to focus on
breast cancer. I talked to lots of people in this field. Breast cancer support
group organizers. Foundations. Not much happened.
I went to the University of Arizona Cancer Center and talked to
its head, Sydney Salmon, M.D.
He said something like this: "Yes, I can see how insulin might
have the effects that you are describing. But it is not a new drug, so no one will
make any money from it, and so you will have difficulty finding funding for it.
On the other hand, if you were to come to us with, say, thirty thousand dollars, I have
someone on the staff here who would certainly be interested in looking into it."
I was grateful to have such an honest assessment and explanation of how the
established research system works. Ironically, he died of pancreatic
cancer in 1999, probably without ever having read our case studies of
pancreatic cancer sent into complete remission using IPT.
I talked with some other high level cancer researchers at the University of
Arizona Cancer Center, David Alberts M.D. and
Dorr Ph.D., and they actually tried some simple petri-dish experiments, with a
drug they were funded to study, but without
promising results. I have not reviewed their experimental design,
but I suspect that it had limitations.
For me, it was an exciting time. I
made IPT the main focus of my actions. During the day I would write letters and make
phone calls. At night I would stay up late doing research in the University of
Arizona medical school library, finding references for Steve's papers. At
conferences I would approach doctors and researchers.
October 24, 1988
Dr. Christopher Duffield, Ph.D.
402 North Main
Tucson, AZ 85701
Dear Dr. Duffield:
On behalf of William H. Gates, Chairman of Microsoft Corporation, I must decline
investment in Insulin Potentiation Therapy technology. After reviewing the
information you provided, Mr. Gates does not feel it is compatible with his personal
Susan F. Raunig
CHAIRMAN AND CHIEF EXECUTIVE OFFICERApril
Dr. Christopher Duffield
402 North Main Avenue
Tucson, Arizona 85701
Dear Dr. Duffield:
Thank you for your letter of April 1st which I reviewed with care and interest.
The work described therein may indeed well have some substance; however, to bring it to
the United States, manufacture the drug, test it on a large number of patients, etc.,
would entail, as you no doubt realize, quite a costly operation.
Notwithstanding, because I am Chairman of the Presidents Cancer Panel, I am
ethically bound not to involve myself in any projects which may have commercial
applications in the field of cancer.
While I regret that I cannot be of assistance, I appreciate your writing me and
sincerely hope that you will be able to find a way to carry on with your work.
AH : cmj
We tried contacting celebrities. I
wrote to actress Lee Remick, my third cousin, about IPT. She had cancer, and was kind enough to write back to me. Her doctor was apparently
skeptical. She died later. I sent an information package about IPT and AIDS to
Elizabeth Taylor and her foundation for AIDS research. Never heard back. We
sent information to actor Michael Landon, who was dying of supposedly untreatable
pancreatic cancer, telling him about IPT as a possible effective treatment for that
disease. IPT almost got selected for his last efforts, but another therapy won
out. I sent information to Bill Gates. His assistant wrote a form letter
back: No. I wrote twice to billionaire Armand Hammer, an acquaintance of
my biological father's, who had stated publicly that he wanted to devote the rest of his
life to finding a cure for cancer. He wrote back: No. I wrote to President
Bush, and an assistant sent me an NIH grant application.
Then there was the time I got a call from a
Hollywood promoter who wanted to put on a celebrity IPT telethon. He talked me into
buying a plane ticket to L.A. There he introduced me to his money man at a window
table with a spectacular view, at the penthouse restaurant/bar atop the round hotel tower
overlooking I-405 beneath the site of the new Getty Museum. The money man, who used
this table as his office for all the day's meetings, explained how he worked. He
would be very happy to lend us the money for the telethon, if we would pay him his large
amount of interest up front, and then pay him back the principal after the show. My
intuition bristled -- what if the event flopped? -- and I got out of there.
Dr. Perez Garcia 3 moved from Mexico
City to Tijuana in 1988. Once, I went there to try an IPT
treatment for myself. Not having a serious disease, I decided to be a guinea pig and
try potentiating cognition enhancing drugs. This was in the days of a mandatory
enema before the treatment. (Thank goodness that is no longer necessary!) The
nurse had me put on a gown and get in bed. She hooked me up to an IV drip.
Donato injected regular insulin into the IV line, and gave me tablets of two drugs -- I think they
were Piracetam and Centrophenoxine. Over the next half hour the insulin took effect,
at first not noticeable, then speeding up. I became drowsy and my pulse speeded
up. I saw some green phosphenes -- less glucose getting to my brain. I began
to have a hard time thinking and talking. It felt like I was distant from the room,
slowly and comfortably drifting away from this world.
The "therapeutic moment"
arrived: Donato injected some liquid vitamin C -- and I could smell and taste it, an
unexpected sensation, as the blood carried it past my olfactory nerves and taste
buds. Then vitamin B complex -- a very strong and different smell. And finally
glucose, which brought me back to normal awareness in just a few seconds. I actually
had some mild symptoms (a slight headache, as I recall) that I had read were symptoms of
overdose for one of the drugs. Donato had given me a normal dose, and IPT had made
it into an overdose. At a drugstore I bought some nutrients (lecithin among them)
that are the antidote for such overdose, and after I took them, I felt really
wonderful for the rest of the day, and very good for days afterward.
According to Dr. Perez Garcia 3's records, the other medications administered to me in my first
(and so far only) IPT treatment were:
Oral: 40 mg of Undecanoato de testosterona
100 mg of Nimesulid -antinflamatory-
150 mg of Ranitidina -for gastric irritation-
0.70mg of Yodocaseina -immunologic booster- no longer available
IM: Liver Extract 2 cc - liver protection
IV: 40mg of Cocarboxilasa - memory enhancer
1 gr of Vitamin C
1 ampule of Magnesium & Calcium Gluconate
Drug companies fund most pharmaceutical
research. So we tried contacting drug companies. An insulin
manufacturer, drug companies that make drugs that work well with IPT, companies that
had experimental drugs that worked well in the test tube but had bad side effects which
IPT might be able to eliminate. No luck.
As a 1971 alumnus of Amherst College, which
has many rich and powerful alumni, I tried following up on some Amherst leads. The
old boy network was only modestly productive. Our class agent refused to print my
story about IPT in the alumni magazine. I wrote an impassioned letter to David
Kessler, class of '73, head of the FDA. A staff person got back to me, explaining that
they were aware of Dr. SGA's efforts, but could not discuss the situation with
me. (In 1996, at my Amherst reunion, I tracked down Dr. Harold
of '61, Director of the National Institutes of Health. I intercepted him on the way
to dinner, and gave him my 60 second speech about IPT. He sort of snorted
and sneered and
suggested that I apply for a grant like everyone else.) My classmate Bob
very big in NIH's AIDS efforts, was skeptical about IPT. So was Teller, of Penn
& Teller, class of 1969. Teller, normally silent on stage, sent me a postcard
saying that I should be careful about making unrealistic claims! To paraphrase a
Penn & Teller show title: Don't try IPT at home.
MRF letterhead logo
I finally scored with Rich
Moret, also class
of 1969, a public relations and advertising man in Tucson. He gave us free advice
and free help, and some free office space that we never really used. He connected us
with a small group of wealthy Tucsonans. Dr. SGA, Mel, and the Drs. Perez Garcia
flew into town
to meet with them. We paid for a fancy lunch at a private hotel dining room.
I'll never forget the uniformed waiters lifting the silver covers off all our plates at
the same instant. We asked the people for a donation. They said "Let's
make money with this instead." So we switched to proposing a joint venture
clinic in Tijuana. More faxes, more phone calls, more business plans. And
nothing ever happened.
Rich also helped us place an ad in the Los
Angeles Times on a Sunday. It was a small ad, about 3 x 5 inches, offering free
breast cancer treatment to women as a clinical trial. It cost us about a thousand
dollars, out of our own pockets, of course. I was ready and waiting, in my
grandmother's basement, for the onslaught of desperate patients and clamoring press reporters,
with two 800 numbers and a new telephone headset. We got something like 18 calls,
from doctors and potential patients, and no one was interested enough to follow through. We placed some more ads in a
Palm Springs magazine. No calls. And some more ads in some LA weekly
newspapers. Same result.
In the mean time, Mel insisted that we needed an
office in downtown San Diego. And over my strenuous objections, we got one in a high
rise. It was very expensive, and the rent came out of our pockets.
Not so much out of mine, because I was almost broke. Mel was the only person who
ever used that office. As I recall, he started flying to San Diego a couple of times
a month to help with MRF business, but apparently also to try to expand his patent
business from the east coast.
I did have some success in San Diego.
An older Amherst alumnus kindly donated about $2,000 worth of stock to MRF, the only
outside money we ever received for either SANA or MRF. Unfortunately, it all went to
pay old bills. And an executive at Scripps Clinic gave me a lead to the president of
Johnson & Johnson. I called him up, and he said he was interested. But I
was burned out by that time, and was losing trust in our team, and did not follow through
with an information packet. I've always wondered what might have happened if I had
There came a moment when Mel,
Dr. SGA, and the Drs. Perez Garcia and their wives were all in Tucson, for meeting with Rich Moret's potential
donors. And my 89-year-old grandmother was in her bedroom, slowly dying of her final
illness. (She had patiently supported me and listened to me and encouraged me
throughout the whole SANA/MRF adventure. Only because of her could I have
become involved.) I brought everyone to the old house, but they did not feel
right about going inside, and she never got to meet them. We took a group picture
out on the lawn. A few weeks later, I was with her during her final breath, there in
the same bedroom where she was born. It turns out that she may have had colon
cancer. If IPT had been available, she might have lived a while longer.
Finally, it all fell apart in the early
1990s. The office in San Diego was the last straw that broke us. The
Drs. Perez Garcia rebelled, and we shut it down. There were angry phone calls and
letters all around. Communication broke off. Dr. SGA kept SANA going
in name as his personal project, eventually closing it in 1997. MRF died, and became
a mere paper entity in my basement, as I tried to recover my personal finances after my
grandmother's death. The Drs. Perez Garcia were doubly burned. Not only had they spent
many thousands of dollars of their own money on unnecessary expenses, but they were taxed
severely and unjustly by the Mexican IRS on the entire MRF cash flow, because their names
were among those on the bank account. We blew apart like chunks of an exploding
airplane, each still committed to IPT, but making our efforts part time and on our own.
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