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"The biggest changes of all will be in the arena of medicine.  It's so astonishingly primitive today, it really is ripe for change."    -- Paul Saffo, Director, Institute for the Future, predicting how the world will be different 100 years from now (San Jose Mercury News, March 12, 1999, page a4).

        The field of IPT applications is so huge and diverse that we can only outline here some major directions for IPT research.  As IPT information proliferates, and as interest in IPT grows, the brightest minds in many fields will see new IPT-related problems to investigate in their own domains.  It will be a very exciting time.

        The best way to ensure that this research will get done is to let people know about IPT and IPTQ.com.  The easiest way is to send them an email.

Major directions for IPT research:

Documenting IPT as it was and is
Laboratory research
Medical literature research

Clinical research
Social, economic, and political research
A few research ideas

bulletDocumenting IPT as it was and is.   The importance of this cannot be overemphasized.  In more than 120 man-years of clinical experience, the IPT doctors have tried a lot of things and have observed a lot of things.  Even among the four long-term practitioners (only one still living), there have been differences and evolutions of models and assumptions.  If we start by focusing on just one set of models and assumptions, we will miss out on the others.  For example, there seems to be a trend towards simplifying the procedure to make it more like standard medical practice, in which only one drug or a few drugs are given for a disease, along with the insulin.  We might lose a lot if we ignore the successes of the early practitioners in detoxifying the body and improving general health, by using complex and comprehensive cocktails of medications, only a few of which might be ordinarily indicated for the presenting illness.

       Donato Perez Garcia MD 1 (1896-1971), the discoverer of IPT, left behind written records of his work.  Much of it is available now on IPTQ.com, but much also waits for scanning and translation.

        Donato Perez Garcia y Bellon MD 2 (1930-2000), was born into the world of IPT, practiced IPT for 44 years, and worked side-by-side with his father for 16 years.   He was our living link to the origins of IPT, before any assumptions were made.  Including his father's experience, Dr. Perez Garcia y Bellon 2 represented 87 years of clinical experience with IPT, more than 60 percent of all the experience to date.  He and his father applied IPT to more different diseases than anyone else ever has.  Like the last surviving healer from an ancient tribe in the Amazon, Dr. Perez Garcia y Bellon 2 was a living encyclopedia, a world treasure, an irreplaceable resource.  Now, due to his recent death, on November 23, 2000, we have missed our chance to debrief him about his life's mission.  We need to preserve and study his papers.  Much of his work is available now on IPTQ.com, and much more needs to be scanned and translated.  His patient records, if they can be saved, will provide a valuable resource for medical researchers who want to know how he and his father treated diseases other than cancer and arthritis.

        Donato Perez Garcia MD 3, is very energetic, and is ready to teach IPT as he practices it, and to participate in IPT research programs, especially in Europe and the United States.  With 17 years of experience, including five years working directly with his father, he knows more about IPT practice than anyone now living.  

        The papers of Jean-Claude Paquette MD do still exist, thanks to the kind intervention of his son Louis Paquette.  His notes and his patient files could provide some very valuable insights into whatever IPT innovations he made.  And it would be wonderful to know exactly which medications he used for the spectacular cases he presents in his book, Medicine of Hope, published on IPTQ.com in English translation by Aimé Ricci.


bulletLaboratory research  Much work needs to be done to clarify the mechanisms of IPT action.  We have a lot of ideas, and a lot of pieces of this biomedical puzzle.  But the vast majority of these pieces were gathered by people who did not know about IPT.  Knowing about IPT will help researchers ask more pertinent questions and try more IPT-relevant experiments.  This could be a big field.  It is not hard to foresee big scientific conferences on IPT.

        It is important to stress the importance of doing much IPT research in animals (even though we are very sensitive to the concerns of many people about the ethics of this).   Insulin clearly does a lot of things in the mammalian body, and many of these things take place on the level of the whole organism.  Cell and tissue  models, in vitro, are of great value, but they cannot substitute for work with living animals.
bulletMedical literature research.  Just give me a couple of biomedical research associates or graduate students and we can do wonders just by searching through Medline.  A few brief forays into the medical literature there have convinced me that much of the laboratory research we need has already been done, that it just needs to be examined and reinterpreted in light of the experiences of IPT doctors.  Also scanning the literature will provide insights about how the IPT protocol and its medication combinations can be improved.  And it is very likely to suggest new applications for IPT.  This could lead to publication of a lot of papers.
bulletClinical research  Since IPT is apparently so safe and benign, there seems to be little keeping doctors from practicing it right now.  Little except not knowing about it.  Some research doctors will want to test IPT in controlled clinical trials.  And  other doctors will want to just jump in and start treating patients in their private or institutional practices.  Funding mechanisms are already in place.  Institutions are already in place.  Mechanisms are already in place for gathering results and information from both pathways.  As IPT catches on, we can foresee a biomedical scientific society forming around it, and probably at least one journal.  And as IPT is applied to one disease after another, articles will appear in many different specialized publications.
bulletSocial, economic, and political research.   Since IPT could represent a significant evolution in medical treatment, with social, economic, and political repercussions, it is a great subject for social science research.  What will happen as IPT is introduced?  What can be done to aid its implementation?  What ethical issues are brought up by its introduction, and by its widespread ignorance for the past 70 years?


Here are a few IPT research ideas:

Find the optimum timing for IPT -- administration of drugs, insulin, and glucose.

Explore the effects of different doses of the ingredients.   What are the optimum levels?

What determines if a drug is better suited for IPT use?

Are there better mechanical ways to deliver the therapy?  Perhaps adaptations for emergency field use, for use in developing countries, for veterinary use? 

Gene chips to study expression of genes  in different tissues during IPT, to better understand the mechanisms involved.

Gene chip or other assay to determine a patient's susceptibility to IPT, and perhaps to determine doses and timing. 

New drugs that are optimized to work with IPT.

Old drugs that were too toxic, that can be revived to work with IPT.

Can IPT mechanisms be traced back to pre-mammalian life forms such as nematodes?  Can we improve IPT based on this knowledge?

Can IPT help prevent spinal cord damage after spinal injuries, and can it help recover function after paralysis?

Does IPT stimulate proliferation and differentiation of stem cells, leading to healing and regeneration?

Can IPT counteract the effects of antibiotic resistance of bacteria, viruses, and parasites?

Can IPT counter drug resistance of malaria parasites by increasing absorption of drugs into cells?

Does IPT improve treatment of gum infections?

Can IPT improve the survival rate of heart patients?

Can new medical devices be developed that assist and automate the IPT process?  Perhaps timed IV pumps that sense blood sugar and inject all the components at the proper time.

What is the scientific explanation of the "Oncodiagnosticator" developed by Drs. Perez Garcia 1 and 2, and can it be simplified, perfected, and developed into a practical laboratory test?

This list could (and will) go on, and on, and on...


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