Sepsis and septic shock are severe
reactions to infection in the body. In sepsis, inflammation in reaction to
the infection triggers a cascade of blood coagulation, which can lead to
multiple organ failure and death. Sepsis may be the most common cause of
death in intensive care units, with mortality of 40%. More than 500,000
people per year develop sepsis in the US, with mortality of 35 to 45%. No
specific treatment is known.
I suggest (11/4/2000) that IPT
could be a part of or even the basis of successful sepsis treatment. IPT
has certainly been shown, anecdotally, to work rapidly and effectively to
deliver drugs better into isolated compartments of the body, and to boost the
effectiveness of antibiotics and anti-inflammatory drugs. Cases of IPT
treatment of appendicitis and necrotic and ischemic injuries suggest that it
might work in sepsis patients as well.
A good place to start would be to
use a combination of antibiotics, anti-inflammatories, and possibly
anti-clotting factors along with IPT. The antibiotics would be to quickly
end the causative infection, wherever it may be, even if it is hidden and
unknown, as it is in 20 to 30% of cases. This alone might stop sepsis in
the early stages. The anti-inflammatories would suppress and moderate the
inflammation, and help quiet and rebalance the immune system. And the
anti-clotting factors would help restore normal coagulation function of the
blood. Biomedical professionals and experienced IPT doctors (the Drs.
Perez Garcia) will have ideas for other beneficial agents to add to the IPT
treatment; I am just suggesting the most obvious ones.