Cardiovascular Disease and IPT
One of the most important applications of IPT may turn out to be in cardiology.
The Drs. Perez Garcia and Dr. Paquette have apparently had some successes in this realm,
although it has not been the major part of their practices. There are many
clues that further investigation of IPT for cardiology may be in order.
Dr. Paquette, in his book Medicine of Hope,
reports a case of a patient with myocardial
infarction (heart attack), ischemic lesion of the heart muscle, and left cardiac
insufficiency. The patient was about to accept a coronary bypass
operation. After IPT treatment, in less than 10 days, all symptoms
disappeared: precordalgia, numbness, dizzy spells, edema, cyanosis,
dyspnea with effort (difficulty breathing), and tension headaches. Seven
months later, he no longer needed surgery, and his cholesterol level was
returned to normal.
- The rapid and wonderful results of IPT for vascular disease in other
parts of the body (see Vascular page).
The reported rapid disappearance with IPT of many vascular symptoms that
cardiologists monitor: high cholesterol, edema, unbalanced
- The use of insulin in solutions to keep solitary organs (including
hearts) alive for transplantation.
Apparently the insulin, by increasing cell permeability, helps
supply nutrients to cells and helps remove toxins from them without
benefit of circulation. Such cell permeability would no doubt be of
great use in a heart, still in the body, which has impaired circulation.
- The rapid healing of injured muscles, reduction of scars, and increased
circulation with direct injection of small amounts of insulin, as reported
by the US insulin study group of the 1930s, as reported in a 1977
article by Hal Huggins.
- Insulin's known role as a cell growth factor and a stimulator of angiogenesis
(growth of new blood vessels), both directly, and by cross-reaction with
insulin-like growth factor 1 (IGF-1).
- The apparent ability of IPT to stop inflammation and speed healing in
cases of arthritis, and even necrotic bone (see Arthritis
- The work by Demetrio Sodi Pallares MD in
Mexico City on using GIK solution
(glucose-insulin-potassium) for emergency cardiology treatment. See
evidence that perhaps 80 percent of atherosclerosis and heart
disease may be caused by Chlamydia pneumoniae, a species of
bacteria that may enter the bloodstream through the lungs, or even through
gum infections. IPT may be an ideal way of rapidly treating systemic
infection with this bacterium, as both treatment and prevention for heart
- Rapid clearing of stroke-related paralysis (see Stroke/Paralysis
page) with IPT may indicate multiple mechanisms at work, including
nerve cell regeneration, and improved circulation. Perhaps IPT can
help reduce arrhythmias.
- A recent paper (Matthews KG, et al, J Endocrinol 1999 Dec;
163(3):433-445) shows that IGF-I and IGF-II are apparently closely
involved in heart muscle events after infarcts (circulation blockages) in
many roles, not only in the heart muscle cells, but also in macrophages
(immune cells). The authors hypothesize that these growth factors
help maintain heart function by inducing swelling (hypertrophy) and
increasing cell survival by decreasing programmed cell death
(apoptosis). It is known that insulin can cross-react with IGF-I and
IGF-II receptors, so externally applied (exogenous) insulin may help
stimulate these same healing processes.
Here are my brainstorms about how IPT could be applied in the cardiology of the
future. I welcome dialogue, and hope that this may stimulate some further
- Prevention. Where there is indication of Chlamydia
pneumoniae infection in the circulatory system, perhaps indicated by
antibody tests, a prophylactic course of antibiotics (perhaps azithromycin)
potentiated by IPT could perhaps clear the system and prevent disease.
- Emergency treatment. GIK may be an effective treatment to
increase survival rates during and after heart attacks. But IPT may
actually turn out to be better, resulting in more rapid balancing of
blood chemistry, and deeper systemic penetration of insulin, glucose,
electrolytes, anticoagulants, and other medications to improve
circulation, reduce swelling and shock, reduce inflammation, and speed
healing. Perhaps IPT added to streptokinase treatment would help
obtain better results with less toxicity. Magnesium is apparently
helpful for keeping heart cells alive, so this could be added to the IPT
- Chronic treatment. Standard IPT treatment, perhaps with
antibiotics to clear Chlamydia pneumoniae infection. If
results like those reported by Dr. Paquette are obtained, both patients
and doctors will be very happy.
- Pre-surgery preparation. Perhaps IPT immediately before
surgery (if it cannot be avoided) will reduce the doses and side effects
of anesthesia, and will prepare the entire body for a longer period of
reduced circulation and reduced oxygen. It may also reduce