Cellular Cancer Therapy, part 15

Case History # 16         Seminoma of the left testicle

Name: C V G         Date: July i6, 1961

Age: 6o                     Sex: Male

Weight: 40                 Height: 1.74 in

Profession: Barber

Previous History:    The patient relates that one month ago he awoke in the middle of the night with a sharp piercing pain in the testicle; since then a tumor has appeared and begun to grow. He consulted various physicians, all of whom suggested that he be operated on, as it was a. case of testicular carcinoma. The patient now weighs 40 kg where two months ago he weighed 84 kg. The tumor is the size of an orange. The intense and continuous pain is not only localized in the testicle but is radiating to the whole body.

Specific Symptoms:    The patient has to urinate lying down. The penis is not readily seen, as it is lost in the swollen tissue of the scrotum.

Physical exploration:    The left testicle is the size of an orange and is very painful to the touch; the vas deferens has greatly increased in volume up to the inguinal canal. The inguinal region hard, painful, irregular lymph nodes are palpated that are the size of marbles.

Diagnosis:    Seminoma of the left testicle with metastasis to the corresponding inguinal lymph nodes.

Treatment:    We administered 7 sessions of Donatian therapy. After the second session, there was a marked improvement, with substantial reduction in the size of the tumor.

On October 23 the patient was released; all signs and symptoms had completely disappeared.

Evolution of Treatment:    The results of the first treatment were that the pain in the testicle became less intense and intermittent, the testicle was reduced to the size of a lime, the vas deferens was more easily palpated since it had also been reduced in volume, the inguinal lymph nodes were round, less painful, softer and the size of beans. The patient began to feel his appetite return.

After the fourth treatment, the pain that radiated to the whole body was only present in the left testicle, greatly reduced in intensity, and the testicle was reduced to the size of a marble; the vas deferens is no longer inflamed or painful; the inguinal lymph nodes are the size of the head of a nail.

At the time of the last three treatments, and especially the last (the seventh), the patient showed no signs of tumor in the testicle; on palpation it was found to be normal, not painful, and with its other normal characteristics; the inguinal lymph nodes disappeared and showed no signs or symptoms. The patient was released in October of the same year, completely cured.

Case History # 17         Lymphocytic lymphoma.

Name: M T A         Date: April 23, 1971

Age: 70                     Sex: Female

Weight: 61                 Height: 1.59 m

Profession: home

Previous history:    Had a total hysterectomy 18 years ago. Menopause occurred at 45, after having given birth to 9 children.

Piercing pain in the left cheek began in October of 1970; the patient’s face began to swell after the onset of pain; as it swelled, the cheek became very hard.

Initially the pain was local, but later it radiated to all of the head and the teeth, to the point where it was no longer possible to chew food. Since the tumor continued to grow, the patient went to the Oncology Institute where she was operated on and the tumor was removed. Biopsy revealed that it was a not very differentiated stage II lymphocytic lymphoma.

A few weeks later the swelling began again in the face, the tumor developed and painful lymph nodes appeared in the left axilla.

Physical Exploration:    Tumor in the region of the left cheek, ulcerated and producing a creamy yellow liquid with a fetid odor. The tumor reaches the lateral face of the nasal pyramid and is the size of a walnut. There are swollen lymph nodes in the submaxillary region on both sides that are hard and painful.

Fourth degree Systolic murmur in the aortic focus. BP 178/106

Diagnosis:    Second degree lymphocytic lymphoma.

Treatment:    We administered 10 sessions of Donatian therapy, one per week. The patient was released on July 10, 1971; the attached biopsy reveals the absence of malignant tissue.

Evolution of treatment:    The first treatment was on April 23, 1971.

The results of the first treatment were that the pain was less, as was the swelling; the ulcer changed color and oozed less; the tumor was also smaller. Upon physical exploration, the submaxillary lymph nodes were not as hard or painful, as was the case with those in the left axilla.

After the fourth treatment, the ulcer on the left cheek showed the formation of new epithelial tissue, the pus was no longer yellowish or fetid and the tumor was the size of a marble; nor were those of the right submaxillary region; the lymph nodes of the left submaxillary region were still present but very small.

After the eighth treatment the patient showed no more symptoms. After the last two treatments, the histopathological examination reported an absence of malignant neoplastic tissue, with which the patient was released, totally cured, on July 10 of that same year.

Case History # 18         Thyroid carcinoma

Name: N G Z         Date: April 30, 1962

Age: 52                 Sex: Female

Weight: 37 kg         Height: 1.60 m

Profession: home

Previous history:    Two years ago a tumor appeared on the left side of the thyroid glands, that sometimes burned and caused the patient pain. In two months the tumor grew to the size of an orange. The local doctor operated, after which she felt well for about a week. Then the tumor and symptoms appeared again but with more intensity. She came to consult a specialist who prescribed radiotherapy.

The radiotherapy was of very high voltage, with two tangential fields; the patient received a total of 2200 r in each field at 220 kv and 15 mA, using a 0.5 mm Copper filter.

Subsequently the patient worsened and the surgeons and radiologists considered her incurable.

The patient arrived at our clinic on April 30, 1962, with more intense pain; she could not chew, there was dysphagia and dysphonia. She had lost 10 kg in the last 3 months.

Physical Exploration:    A tumor is palpated under the left maxilla. The patient cannot open her mouth very well. The tumor takes up a large part of the neck and is of a wooden consistency; it is attached to the trachea and is approximately 9 cm long by 6 cm wide, and very painful. BP 145/85

Diagnosis:    Thyroid carcinoma

Treatment:    We administered 20 sessions of Donatian therapy, May 1 to July 31, 1963.

From the 15th treatment on, the patient complained of no discomfort; the tumor had disappeared. Upon completion of the treatment, the patient was released, totally cured.

Case History # 19         Gastric carcinoma

Name: B T C         Date: June 9, 1972

Age:  67                 Sex: Female

Weight: 63 kg          Height: 1.65 m

Profession: home

Previous history:    Menopause occurred at the age of 50, after having had 5 children. The patient tells us that upon returning from a vacation she began to feel pain in the stomach, with nausea and vomiting of phlegm, as well as gradual loss of appetite. She consulted a physician who prescribed Melox. The pain disappeared, but she continued to have no appetite. Several weeks elapsed in this state, until the same symptoms reappeared. She consulted another physician who ordered a gastroduodenal series of x-rays and the diagnosis was gastric carcinoma.

Symptoms:    Complete anorexia, continuous piercing pain in the epigastrium which causes nausea and vomiting; upon vomiting the pain disappears or becomes weaker but returns full force minutes later.

Physical Exploration:    There is splenomegalia, the epigastrium is very painful. The x-ray with the date May 30, 1972 shows an exophytic growth which affects the major and minor curves in the medial third of the longitudinal diameter of the stomach.

Diagnosis:    Second degree (Borman’s classification) gastric carcinoma.

Treatment:    We administered 11 sessions of Donatian therapy, one per week. Another gastroduodenal series of x-rays was taken on July 25, 1972, when the treatment had not yet been completed and the patient already had a normal stomach. She was released on August 30, 1972 totally cured.

Evolution of Treatment:    The first treatment was on June 9, 1972. As a result of the first treatment, the pain in the epigastrium and the vomiting disappeared; the nausea persisted but with less intensity. After the fifth treatment, the patient recovered her appetite, though the nausea persisted. The patient reports that the pain only recurred once, but with less intensity. After the tenth treatment the patient showed no symptoms, but a gain in weight. After the eleventh treatment another gastroduodenal x-ray series was ordered which confirmed her stomach to be normal.

Case History # 20             Epidermoid carcinoma with metastasis

Name: M R de la F         Date: June 2, 1971

Age: 37                             Sex: Female

Weight: 65 kg                     Height: 1.71 m

Profession: home

Previous history:    The patient tells us that she underwent oophorectomy and mastectomy of the right breast because of an epidermoid carcinoma and metastasis. Since the time of the operation the wound has not healed properly: there is a purulent secretion, pain, and in the place of the scar there is a hazelnut-sized tumor.

Treatment:    We administered 14 sessions of Donatian therapy, starting on July 1, 1971. At the end of three months treatment, the patient was released, cured.

The patient lived for eight years, after which she died of a metastasis to the lung for which she did not come to us but was treated at another clinic.

Case History # 21         Ewing’s sarcoma

Name: M G P         Date: August 18, 1970

Age: 3                         Sex: Female

Weight: 18 kg             Height: 1.09 m

Previous history:    The patient’s mother tells us that the girl had, two months ago, what appeared to be a Colles’ fracture of the left wrist. The first physician that they consulted put the left forearm in a cast, but as time went on the girl did not get better and the wrist continued to be swollen.

The parents consulted another physician who performed a biopsy of the radius of the left forearm. The result was: Ewing’s Sarcoma.

Since then, the destruction of the bone has become more aggressive; x-rays show the extension of the neoplasia, with metastases to the larger bones. The girl was given up on and the parents came to us.

Symptoms:    Loss of 4 kg of weight, as well as the other symptoms mentioned: pain, edema of the left wrist, slight fever.

Physical Exploration:    BP: 80/40 Pulse: 90/min Temp: 37°C

Hard, painful lymph nodes are palpated in both submaxillary regions; they are the size of grapes. The supraclavicular nodes are also swollen, as are those of the neck.

The area of the elbow has three small, hard painful lymph nodes; the wrist is swollen, and deformed in varus and adduction, with intermediate pronation. There is very intense pain upon palpation.

Diagnosis:    Ewing’s Sarcoma

Treatment:    We administered 17 sessions of Donatian therapy, over a period of months. On February 12, 1971, x-rays were taken of the patient’s whole skeleton, All of the bones were normal, The patient was released, cured.

Evolution of Treatment:    The first treatment was on August 18, 1970. The result of the first treatment was that the pain and edema diminished, the patient’s appetite improved, the fever began to come down. Upon physical exploration the submaxillary lymph nodes seemed to be less painful and the right one was smaller than the left; the supraclavicular nodes were reduced to the size of pin-heads; the lymph nodes of the elbow were not as painful, and their size and consistency were reduced.

After the fourth treatment the pain was intermittent and slight; the edema has completely disappeared and the left forearm and wrist returned to their normal anatomical positions. Upon palpation intense pain is no longer present, and the retroinaxillary lymph nodes are reduced to the size of lentils. The supraclavicular nodes are also smaller, but the right one is smaller than the left; the fever has not returned; the lymph nodes of the elbow do not hurt and are reduced in size and consistency. X-rays of the forearm showed a possible neoformation but not a Ewing’s sarcoma.

After the eighth session, the intense pain in the left had disappeared completely; the retromaxillary lymph nodes were no longer painful and the right one disappeared; the left one was the size of a pin—head. The supraclavicular nodes disappeared as did those of the elbow. Another x-ray of the left forearm and hand was ordered which showed a marked improvement of the lesion over previous x-rays.

After the twelfth session, the girl showed no problems with her left wrist or forearm. The five final treatments were administered and x-rays taken of the patient’s entire skeleton and she was released, totally cured.

After eight years, the case is still totally cured.

Case History # 22         Metastasis of adenocarcinoma of the gall bladder

Name: E H A         Date: June 8, 1964

Age:  55                     Sex: Female

Weight: 69.85 kg         Height: 1.66 m

Profession: businesswoman

Previous history:    One year ago the patient began to feel pain in the epigastrium, near the liver, accompanied by a sensation of distention and very intense nausea. Seven months later she became icteric all over her body. On April 10, 1964 a cholecystectomy was performed. A biopsy was done with the sample removed and the result was a semi-differentiated infiltrating adenocarcinoma of the gall bladder. Cholelithiasis.

After the operation total icterus continued. The intense pain persisted. Exhaustion is more marked now than before the cholecystectomy; there is also a continuous fever of 38°C and edema of both legs. Besides the nausea, vomiting has appeared.

Physical Exploration:    BP: 90/40

Painful and intensely jaundiced appearance; the patient looks cachectic, makes an enormous effort to take a step.

The abdomen is convex with a scar approximately 30 cm long that goes from the epigastrium, almost parallel to the right costal edge, to the anterior superior illiac spine where there is a tube for drainage that is releasing a yellow sanguinolent liquid. Extraction of the drainage tube does not produce pain. The epigastrium and right flank are very elevated.

There Is hepatomegalia and splenomegalia, very much gas in the abdomen and edema in both legs. The bilirubin is at a level of 1.75 mg/100 ml, alkaline phosphatase is at 1200 lU/liter, and cholesterol at 329 mg/100 ml.

Diagnosis:    Metastasis of the semi-differentiated infiltrating adenocarcinoma of the gall bladder.

Treatment:    We administered 5 sessions of Donatian therapy, one every three days. Twenty-one days later the patient weighed 55 kg, icterus had disappeared, bilirubin was at 3 mg/100 ml and alkaline phosphatase was at 105 IU/ml.

The patient is cured, according to clinical and laboratory examinations.

Case History # 23         Epidermoid carcinoma of the cervix. Trichomoniasis.

Name: C B M         Date: June 4, 1964

Age: 32                     Sex: Female

Weight:  51 kg             Height: 1.57 in

Profession: businesswoman

Previous history:    Leukorrhea, since more than a year ago, that is very fetid and sometimes there is a sanguinolent secretion. Bleeding during coitus. Has had 3 hemorrhages in the last three months. Alarmed, the patient consulted a gynecologist, who ordered a Pap test.

The result was a Stage IV epidermoid carcinoma of the cervix. Trichomoniasis. The gynecologist sent her to an oncologist who gave her 15 treatments of cobalt radiotherapy. After radiotherapy, the patient worsened. A new pain appeared in the lower part of the abdomen, there is diarrhea, vomiting, fever of 38°C, continuous vaginal bleeding.

Physical Exploration:    BPs 105/75

Pale complexion, sunken eyes. The cervix is bleeding profusely from the right side where, at 6 and 9 o’clock, one can observe two areas with no mucous membrane that are a tawny red color. The uterus is swollen and reaches to 6 cm below the umbilical scar; it is hard, painful, wooden and inclined in antiversion.

Diagnosis:    Epidermoid carcinoma of the cervix. Trichomoniasis.

Treatment:    We administered 10 sessions of Donatian therapy. On June 22, 1964 another Pap test was performed that gave negative results for malignant cells. The patient was released, cured, on August 10, 1964. She weighed 63 kg upon release.

Case History # 24         Malignant melanoma

Name: E C R         Date: May 23, 1974

Age: 44                     Sex: Male

Weight: 70.6 kg         Height: 1.75 m

Profession: Accountant (CPA)

Previous History:    Arterial hypertension since 1966. Two and a half years ago a mole began to grow next to his left sideburn, about 2 cm from the left earlobe. The patient recalls one occasion when his barber cut the mole and it bled profusely.

Symptoms:    Halitosis, meteorism. BPs 200/124, cephalea, cold feet, slight edema of the feet, nervousness.

Physical Exploration:    A mole located 2 or 3 cm forward of the left ear; approximately 0.5 mm in diameter, purplish color, irregular surface, slight pain upon palpation.

Diagnosis:    Malignant melanoma.

Treatment:    We administered 7 sessions of Donatian therapy, one per week. The patient was examined again on August 23, 1974, and the test with the Oncodiagnosticator was negative. The patient was found to be clinically healthy.

Evolution of Treatment:    The first treatment was on May 23, 1974. After the first treatment the mole was not painful to the touch and was not as purple or inflamed. Cold feet and edema disappeared; nervousness was less; cephalea disappeared; blood pressure went down.

After the fourth treatment, the mole looked like a freckle, was not painful or inflamed and its edges were more regular. Nervousness disappeared.

After the seventh and last treatment the mole disappeared completely; blood, pressure became normal; the patient was found to be clinically healthy. He was released on August 23, 1974, totally cured. We have received no news of any recurrence of symptoms.

Case History # 25         Epidermoid carcinoma

Name: A R A         Date: August 16, 1974

Age: 72                     Sex: Male.

Weight: 80 kg             Height: 1.68 m

Profession: retired train conductor

Previous History:    A spot appeared on the patient’s skin in November, 1973 and has gradually grown.

He consulted a skin specialist, who requested a biopsy to confirm his suspicion of spinocellular epidermoid carcinoma. Biopsy reported a well— differentiated invasive epidermoid carcinoma at the right commissure of the lower lip.

Physical Exploration:    BP: 148/68

On the right side of the lower lip, near the commissure, there is a small, bean-sized tumor. It is slightly purple, with an irregular surface and showing pain upon palpation.

Diagnosis:    Well-differentiated invasive epidermoid carcinoma, at the right commissure of the lower lip.

Treatment:    We administered 12 sessions of Donatian therapy, one per week. The patient was examined on November 18, 1974 and found to be clinically healthy. The test with the Oncodiagnosticator was also negative.

Evolution of Treatment:    The first treatment was on August 16, 1974.

The results of the first treatment were that the tumor was not so painful upon palpation and was slightly smaller; the consistency was the same and the color was a dark brown; the edges and surface were the same.

After the fourth treatment the tumor does not hurt, inflammation is markedly reduced and the color changed to a light brown; the edges are only irregular inside the labial commissure.

After the eighth treatment the tumor is the size of a lentil and there is no pain; inflammation is very slight and the color is a pale brown.

After the twelfth treatment no tumor can be palpated and the patient’s lip is normal. He complains of no discomfort or pain. Another biopsy is done and no malignant cells are reported. He was released on November 28, 1974, totally cured. More recently the patient has communicated with us, and reports that he has had no recurrence of symptoms.