Main sections of this site
About IPT -- Start
of IPT, IPT at a glance, IPT method, How IPT works, IPT experience.
Includes IPT History -- discovery &
origins, 50s-60s, 70s-80s-90s, IPT millennium.
Cancer -- cases
-- breast, prostate, lymphoma, cervix/uterus, skin, bone, pancreas,
colon, nose & throat, other cancers
-- cases & possibilities -- arthritis,
infectious, respiratory, circulatory/cardiovascular, immune/allergy,
neurological, eyes, ears, skin, digestive, genitourinary, musculoskeletal,
currently practicing IPT, and from the past.
Patient Stories --
Interviews with and stories of IPT patients.
Articles & Publications
-- articles, documents, patents, bibliography
Three books about IPT, in English, Spanish, and French.
-- The road ahead for IPT: advocacy,
Open letter to people at pharmaceutical
This website is about a remarkable
medical discovery that you may not be aware of yet. A simple medical procedure involving a pulse of hypoglycemia, created by
insulin followed by glucose...
- Can improve drug delivery into cells, across the blood-brain barrier, and
into less accessible compartments of the body.
- Can greatly improve effectiveness of drugs, allowing them to be given in
smaller doses, or in regular doses with stronger effects.
- Reduces or eliminates toxic side effects of drugs.
- Probably stimulates other beneficial insulin-influenced phenomena such as
angiogenesis, detoxification, stem cell proliferation, etc.
- Has been applied with a wide range of drugs for treatment of
several types of cancer and for a
wide variety of other diseases.
This medical procedure
insulin potentiation therapy (IPT). We think it may be a medical discovery of
great significance, on the level of the discoveries of vaccination,
antibiotics, and insulin itself. I call IPT "The second discovery of
insulin." It has the potential to help millions of people worldwide
The history if IPT is very
interesting, and is marked by three main facts:
- It was discovered in 1926, 75 years ago, and
- It has been continuously practiced with great success by a small but
growing number of private doctors.
- Despite continuing efforts of these doctors to communicate their successes
to pharma companies and government agencies, proper and adequate IPT
research has not yet been done or funded.
What are the reasons for this
third fact? Why has no drug company yet taken concerted action to study
and implement IPT? If you have some new insights into the reasons,
or have some historical information to disclose, please let me know. In
the mean time, my working hypothesis is that each drug company to which IPT was
disclosed dropped the idea for the simple reason that it did not fit in with
their business model. IPT is a method, not a new drug, and so is difficult
to convert into cash flow. And a reduction of drug dose
commonly used in IPT could be
temporarily disruptive to drug markets and might affect short term
profits. The easiest path was to just walk away from IPT and forget it.
This is understandable.
Pharmaceutical companies exist to bring profits to their shareholders. And
in current financial markets, companies are especially focused on
But pharmaceutical companies also
have a responsibility to the human race, of which their employees and stockholders
are members. If IPT is what we think it is, the simple ignorance
of it has had many consequences --- very large ones. It is possible that
75 years of
ignorance of IPT has cost humanity trillions of dollars and millions of
lives. Comparable to the effects of a major war. Conversely, it is possible that IPT research and widespread
implementation could earn humanity trillions of dollars of shared
save millions of lives.
My goal in this letter is to
suggest to you that investment in IPT research and development is now in your
best interest. The humanitarian reasons should be enough. But here are
ten business reasons.
- Good public relations. IPT information is now readily
available on the Internet, and is beginning to appear in the press.
People are finding out about IPT, and will demand that research and
implementation begin. Just as with environmental research
among industrial companies, IPT research could become an essential part of
corporate citizenship among pharma companies.
- Basic science. If IPT is a real phenomenon, then it is
clearly tapping some deep and important mechanisms in the body that are not
yet well understood.
Investigation of IPT would result in a better understanding of these
mechanisms, opening up opportunities for new drug development.
- New large non-diabetic market for insulin. This
should interest Lilly, Novo Nordisk, Pfizer, and any other insulin
manufacturers. One or more of them could also partner with other drug
companies for the next items...
- Extend patents of existing drugs... by
packaging drugs with insulin or glucose for use in IPT, or by adding IPT to
the list of approved uses, or by using other IPT-related packaging or
- Better use of existing drugs. Improved
delivery and effectiveness, with reduced or eliminated toxicity, could enable
drugs to reach their full potential.
- New applications for existing drugs. Improved delivery
and effectiveness of drugs with IPT may make them suitable for
applications which were not possible or practical before.
- Revive drugs rejected for toxicity. Most
drug candidates are rejected, even after costly investment. IPT can reduce
or eliminate toxic side effects, perhaps making these drugs attractive
- Develop new drugs optimized to work with IPT. Take advantage
of this improved delivery method.
- Higher profit per dose. At least in the US, packaging of
smaller drug doses for IPT use could result in a higher profit per dose.
- Open larger markets. Smaller drug doses at lower cost could
greatly expand markets in developing countries and among the poor in rich
These are just preliminary
ideas. You no doubt have a large staff of creative new business
development people who can certainly come up with more reasons for you to get
into research and implementation of IPT, now that it is entering public
consciousness, and won't go away. On deep analysis, I think you will find
that, while IPT might cause some minor market disruptions in the short
term, it will help increase your profits, product success, and public approval
in the long term.
And so, with that introduction, I
invite you to explore the IPTQ.org website. I suggest that you read it
all. Read about things that were presented to your
predecessors in the past seven and a half decades. They took a look, quietly closed the book, and
walked away. Now is your chance to make up for their shortsighted
behavior. Humanity is waiting for you to take this action based on both purely commercial
interests and higher ethical
principles. We will all benefit.
Chris Duffield Ph.D.